The ends of the bones are covered with cartilage. This covering acts like a cushion. This lets the bones move smoothly. Arthritis wears away or destroys the cartilage. Then the bones rub against each other when you move your thumb. This causes the joint to become stiff, inflamed, and painful. This makes pinching and grasping with the thumb and fingers painful. With time, the bone in the thumb may collapse. Then you can no longer straighten your thumb.